diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
index bc3a8db9..f98689d3 100644
--- a/.github/workflows/ci.yml
+++ b/.github/workflows/ci.yml
@@ -120,3 +120,39 @@ jobs:
           make
       - name: "Run test"
         run: make test
+
+  test-tidb:
+    runs-on: 'ubuntu-latest'
+    services:
+      mariadb:
+        image: 'pingcap/tidb:v8.5.1'
+        ports:
+          - 4000:4000
+    steps:
+      - uses: actions/checkout@v4
+      - name: "Setup generic dependencies"
+        run: |
+          sudo apt update
+          sudo apt install -y \
+          gcc \
+          gnupg \
+          libdbi-perl \
+          libdevel-checklib-perl \
+          libtest-deep-perl \
+          libtest-pod-perl \
+          lsb-release \
+          make \
+          wget
+          sudo debconf-set-selections <<EOF
+          mysql-apt-config      mysql-apt-config/select-server  select  mysql-8.4-lts
+          EOF
+          wget https://dev.mysql.com/get/mysql-apt-config_0.8.33-1_all.deb
+          DEBIAN_FRONTEND="noninteractive" sudo dpkg -i mysql-apt-config_0.8.33-1_all.deb
+          sudo apt update
+          sudo apt install -y libmysqlclient-dev
+      - name: "Run build"
+        run: |
+          perl Makefile.PL --testhost=127.0.0.1 --testuser=root --testport=4000
+          make
+      - name: "Run test"
+        run: make test
diff --git a/t/51bind_type_guessing.t b/t/51bind_type_guessing.t
index 2f553ff5..0b3dfd1c 100644
--- a/t/51bind_type_guessing.t
+++ b/t/51bind_type_guessing.t
@@ -22,6 +22,13 @@ if ($dbh->{'mysql_serverinfo'} =~ 'MariaDB') {
   plan skip_all => "This test isn't made to work with MariaDB yet";
 }
 
+# Tested with TiDB v8.5.1.
+# https://github.com/pingcap/tidb/issues/60671
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        "SKIP TEST: test disabled on TiDB";
+}
+
 plan tests => 98;
 
 ok $dbh->do("DROP TABLE IF EXISTS dbd_mysql_t51bind_type_guessing"),
diff --git a/t/55utf8.t b/t/55utf8.t
index 6394b03c..29df37e0 100644
--- a/t/55utf8.t
+++ b/t/55utf8.t
@@ -22,6 +22,13 @@ if ($dbh->{mysql_serverversion} < 50000) {
     plan skip_all =>
         "SKIP TEST: You must have MySQL version 5.0 and greater for this test to run";
 }
+
+# Tested with TiDB v8.5.1.
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        "SKIP TEST: TiDB doesn't support GEOMETRY data type";
+}
+
 plan tests => 16 * 2;
 
 for my $mysql_server_prepare (0, 1) {
diff --git a/t/55utf8_errors.t b/t/55utf8_errors.t
index 5eb9d276..dd2c69ad 100644
--- a/t/55utf8_errors.t
+++ b/t/55utf8_errors.t
@@ -21,6 +21,13 @@ eval {
 if ($@) {
     plan skip_all => "no database connection";
 }
+
+# Tested with TiDB v8.5.1.
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        "SKIP TEST: lc_messages not supported on TiDB";
+}
+
 $dbh->disconnect();
 
 plan tests => 10 * 3;
diff --git a/t/80procs.t b/t/80procs.t
index ad21071d..4eb356f5 100644
--- a/t/80procs.t
+++ b/t/80procs.t
@@ -25,6 +25,12 @@ if ($dbh->{mysql_serverversion} < 50000) {
         "You must have MySQL version 5.0 and greater for this test to run";
 }
 
+# Tested with TiDB v8.5.1.
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        "SKIP TEST: TiDB doesn't support stored procedures";
+}
+
 if (!CheckRoutinePerms($dbh)) {
     plan skip_all =>
         "Your test user does not have ALTER_ROUTINE privileges.";
diff --git a/t/81procs.t b/t/81procs.t
index 91094756..d169767c 100644
--- a/t/81procs.t
+++ b/t/81procs.t
@@ -25,6 +25,12 @@ if ($dbh->{mysql_serverversion} < 50000) {
         "You must have MySQL version 5.0 and greater for this test to run";
 }
 
+# Tested with TiDB v8.5.1.
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        "SKIP TEST: TiDB doesn't support stored procedures";
+}
+
 if (!CheckRoutinePerms($dbh)) {
     plan skip_all =>
         "Your test user does not have ALTER_ROUTINE privileges.";
diff --git a/t/rt118977-zerofill.t b/t/rt118977-zerofill.t
index 27ba1b7f..c55aa3ef 100644
--- a/t/rt118977-zerofill.t
+++ b/t/rt118977-zerofill.t
@@ -10,6 +10,13 @@ require "t/lib.pl";
 my $dbh = eval { DBI->connect($test_dsn, $test_user, $test_password, { PrintError => 1, RaiseError => 1 }) };
 plan skip_all => "no database connection" if $@ or not $dbh;
 
+# Tested with TiDB v8.5.1.
+if ($dbh->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        # https://docs.pingcap.com/tidb/stable/mysql-compatibility/#incompatibility-due-to-deprecated-features
+        "SKIP TEST: TiDB doesn't support ZEROFILL";
+}
+
 plan tests => 4*2;
 
 for my $mysql_server_prepare (0, 1) {
diff --git a/t/rt75353-innodb-lock-timeout.t b/t/rt75353-innodb-lock-timeout.t
index 9c97d60f..0ad9d06d 100644
--- a/t/rt75353-innodb-lock-timeout.t
+++ b/t/rt75353-innodb-lock-timeout.t
@@ -10,6 +10,12 @@ require "t/lib.pl";
 my $dbh1 = eval { DBI->connect($test_dsn, $test_user, $test_password, { RaiseError => 1, AutoCommit => 0 }) };
 plan skip_all => "no database connection" if $@ or not $dbh1;
 
+if ($dbh1->{'mysql_serverinfo'} =~ 'TiDB') {
+    plan skip_all =>
+        # https://docs.pingcap.com/tidb/stable/pessimistic-transaction/#difference-with-mysql-innodb
+        "SKIP TEST: locking behavior on TiDB is different";
+}
+
 my $dbh2 = eval { DBI->connect($test_dsn, $test_user, $test_password, { RaiseError => 1, AutoCommit => 0 }) };
 plan skip_all => "no database connection" if $@ or not $dbh2;