diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 7ee22318fb20d..6176d1506dfbb 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -134,6 +134,9 @@ namespace ts {
         EmptyObjectStrictFacts = All & ~(EQUndefined | EQNull | EQUndefinedOrNull),
         AllTypeofNE = TypeofNEString | TypeofNENumber | TypeofNEBigInt | TypeofNEBoolean | TypeofNESymbol | TypeofNEObject | TypeofNEFunction | NEUndefined,
         EmptyObjectFacts = All,
+        // Masks
+        OrFactsMask = TypeofEQFunction | TypeofEQObject | TypeofNEObject,
+        AndFactsMask = All & ~OrFactsMask,
     }
 
     const typeofEQFacts: ReadonlyESMap<string, TypeFacts> = new Map(getEntries({
@@ -22985,11 +22988,24 @@ namespace ts {
                 // When an intersection contains a primitive type we ignore object type constituents as they are
                 // presumably type tags. For example, in string & { __kind__: "name" } we ignore the object type.
                 ignoreObjects ||= maybeTypeOfKind(type, TypeFlags.Primitive);
-                return reduceLeft((type as UnionType).types, (facts, t) => facts & getTypeFacts(t, ignoreObjects), TypeFacts.All);
+                return getIntersectionTypeFacts(type as IntersectionType, ignoreObjects);
             }
             return TypeFacts.All;
         }
 
+        function getIntersectionTypeFacts(type: IntersectionType, ignoreObjects: boolean): TypeFacts {
+            // When computing the type facts of an intersection type, certain type facts are computed as `and`
+            // and others are computed as `or`.
+            let oredFacts = TypeFacts.None;
+            let andedFacts = TypeFacts.All;
+            for (const t of type.types) {
+                const f = getTypeFacts(t, ignoreObjects);
+                oredFacts |= f;
+                andedFacts &= f;
+            }
+            return oredFacts & TypeFacts.OrFactsMask | andedFacts & TypeFacts.AndFactsMask;
+        }
+
         function getTypeWithFacts(type: Type, include: TypeFacts) {
             return filterType(type, t => (getTypeFacts(t) & include) !== 0);
         }
diff --git a/tests/baselines/reference/narrowingTypeofFunction.js b/tests/baselines/reference/narrowingTypeofFunction.js
new file mode 100644
index 0000000000000..fb38d9249cfa5
--- /dev/null
+++ b/tests/baselines/reference/narrowingTypeofFunction.js
@@ -0,0 +1,40 @@
+//// [narrowingTypeofFunction.ts]
+type Meta = { foo: string }
+interface F { (): string }
+
+function f1(a: (F & Meta) | string) {
+    if (typeof a === "function") {
+        a;
+    }
+    else {
+        a;
+    }
+}
+
+function f2<T>(x: (T & F) | T & string) {
+    if (typeof x === "function") {
+        x;
+    }
+    else {
+        x;
+    }
+}
+
+//// [narrowingTypeofFunction.js]
+"use strict";
+function f1(a) {
+    if (typeof a === "function") {
+        a;
+    }
+    else {
+        a;
+    }
+}
+function f2(x) {
+    if (typeof x === "function") {
+        x;
+    }
+    else {
+        x;
+    }
+}
diff --git a/tests/baselines/reference/narrowingTypeofFunction.symbols b/tests/baselines/reference/narrowingTypeofFunction.symbols
new file mode 100644
index 0000000000000..3bad8d9a42ff5
--- /dev/null
+++ b/tests/baselines/reference/narrowingTypeofFunction.symbols
@@ -0,0 +1,45 @@
+=== tests/cases/compiler/narrowingTypeofFunction.ts ===
+type Meta = { foo: string }
+>Meta : Symbol(Meta, Decl(narrowingTypeofFunction.ts, 0, 0))
+>foo : Symbol(foo, Decl(narrowingTypeofFunction.ts, 0, 13))
+
+interface F { (): string }
+>F : Symbol(F, Decl(narrowingTypeofFunction.ts, 0, 27))
+
+function f1(a: (F & Meta) | string) {
+>f1 : Symbol(f1, Decl(narrowingTypeofFunction.ts, 1, 26))
+>a : Symbol(a, Decl(narrowingTypeofFunction.ts, 3, 12))
+>F : Symbol(F, Decl(narrowingTypeofFunction.ts, 0, 27))
+>Meta : Symbol(Meta, Decl(narrowingTypeofFunction.ts, 0, 0))
+
+    if (typeof a === "function") {
+>a : Symbol(a, Decl(narrowingTypeofFunction.ts, 3, 12))
+
+        a;
+>a : Symbol(a, Decl(narrowingTypeofFunction.ts, 3, 12))
+    }
+    else {
+        a;
+>a : Symbol(a, Decl(narrowingTypeofFunction.ts, 3, 12))
+    }
+}
+
+function f2<T>(x: (T & F) | T & string) {
+>f2 : Symbol(f2, Decl(narrowingTypeofFunction.ts, 10, 1))
+>T : Symbol(T, Decl(narrowingTypeofFunction.ts, 12, 12))
+>x : Symbol(x, Decl(narrowingTypeofFunction.ts, 12, 15))
+>T : Symbol(T, Decl(narrowingTypeofFunction.ts, 12, 12))
+>F : Symbol(F, Decl(narrowingTypeofFunction.ts, 0, 27))
+>T : Symbol(T, Decl(narrowingTypeofFunction.ts, 12, 12))
+
+    if (typeof x === "function") {
+>x : Symbol(x, Decl(narrowingTypeofFunction.ts, 12, 15))
+
+        x;
+>x : Symbol(x, Decl(narrowingTypeofFunction.ts, 12, 15))
+    }
+    else {
+        x;
+>x : Symbol(x, Decl(narrowingTypeofFunction.ts, 12, 15))
+    }
+}
diff --git a/tests/baselines/reference/narrowingTypeofFunction.types b/tests/baselines/reference/narrowingTypeofFunction.types
new file mode 100644
index 0000000000000..86fbf0571fee2
--- /dev/null
+++ b/tests/baselines/reference/narrowingTypeofFunction.types
@@ -0,0 +1,44 @@
+=== tests/cases/compiler/narrowingTypeofFunction.ts ===
+type Meta = { foo: string }
+>Meta : Meta
+>foo : string
+
+interface F { (): string }
+
+function f1(a: (F & Meta) | string) {
+>f1 : (a: (F & Meta) | string) => void
+>a : string | (F & Meta)
+
+    if (typeof a === "function") {
+>typeof a === "function" : boolean
+>typeof a : "string" | "number" | "bigint" | "boolean" | "symbol" | "undefined" | "object" | "function"
+>a : string | (F & Meta)
+>"function" : "function"
+
+        a;
+>a : F & Meta
+    }
+    else {
+        a;
+>a : string
+    }
+}
+
+function f2<T>(x: (T & F) | T & string) {
+>f2 : <T>(x: (T & F) | (T & string)) => void
+>x : (T & F) | (T & string)
+
+    if (typeof x === "function") {
+>typeof x === "function" : boolean
+>typeof x : "string" | "number" | "bigint" | "boolean" | "symbol" | "undefined" | "object" | "function"
+>x : (T & F) | (T & string)
+>"function" : "function"
+
+        x;
+>x : (T & F) | (T & string)
+    }
+    else {
+        x;
+>x : T & string
+    }
+}
diff --git a/tests/cases/compiler/narrowingTypeofFunction.ts b/tests/cases/compiler/narrowingTypeofFunction.ts
new file mode 100644
index 0000000000000..baceaae052222
--- /dev/null
+++ b/tests/cases/compiler/narrowingTypeofFunction.ts
@@ -0,0 +1,22 @@
+// @strict: true
+
+type Meta = { foo: string }
+interface F { (): string }
+
+function f1(a: (F & Meta) | string) {
+    if (typeof a === "function") {
+        a;
+    }
+    else {
+        a;
+    }
+}
+
+function f2<T>(x: (T & F) | T & string) {
+    if (typeof x === "function") {
+        x;
+    }
+    else {
+        x;
+    }
+}
\ No newline at end of file