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| 1 | +#rBatch-run radiomics module inside Slicer using a parameter file |
| 2 | +#Usage: Set variables in slicer console according to local file paths and execute python file. For example: |
| 3 | +#base_directory = r"C:\Users\urs\Desktop\hoedha_radiomics\test" |
| 4 | +#paramfilepath = r"C:\urs\urs\Desktop\hoedha_radiomics\Params_radiomics.yaml" |
| 5 | +#pythonfile = r"C:\Users\urs\Desktop\hoedha_radiomics\radiomics.py" |
| 6 | +#exec(open(pythonfile).read()) |
| 7 | + |
| 8 | +import SlicerRadiomics |
| 9 | +import re |
| 10 | +import pandas as pd |
| 11 | +import openpyxl |
| 12 | +import os |
| 13 | + |
| 14 | +################################SET PARAMETERS########################################### |
| 15 | +#define regex patterns to find correct volumes in scene |
| 16 | +pattern_T1C = r'^(?=.*(?:T1|t1|T1W))(?=.*CE)' #T1C works |
| 17 | +pattern_ADC = r'^\d+:\s.*ADC.*' #works ADC |
| 18 | +pattern_T1 = r'^\d+:\s(T1|t1|T1W)(?!.*CE)' #works T1 |
| 19 | +pattern_T2 = r'^\d+:\s(?!(.*FLAIR.*|.*dark-fluid.*))(T2|t2|T2W)' |
| 20 | +pattern_FLAIR = r'^\d+:\s(FLAIR|.*dark-fluid.*)' #works FLAIR |
| 21 | + |
| 22 | + |
| 23 | +################# Get a list of subfolders in the base directory#################### |
| 24 | +#'base_directory' path is set in the slicer python console |
| 25 | +subfolders = [os.path.join(base_directory, folder) for folder in os.listdir(base_directory) if os.path.isdir(os.path.join(base_directory, folder))] |
| 26 | + |
| 27 | +# Print the full paths of the subfolders |
| 28 | +print('Processing the following folders:') |
| 29 | +for folder in subfolders: |
| 30 | + print(folder) |
| 31 | + |
| 32 | +##############################FUNCTIONS################################ |
| 33 | +#function to find first mrb files in each patient folder |
| 34 | +def find_file_with_extension(directory, extension): |
| 35 | + for root, dirs, files in os.walk(directory): |
| 36 | + for file in files: |
| 37 | + if file.endswith(extension): |
| 38 | + return os.path.join(root, file) |
| 39 | + return None # If no file with the given extension is found |
| 40 | + |
| 41 | +##########################export table to csv############################## |
| 42 | +def savecsvandxlsx(nodename,outname): |
| 43 | + result = getNode(nodename) |
| 44 | + rad_outputFilename = subfolders[Index]+'\\Tables\\'+outname+'.csv' #TAKES i from index of mainloop! |
| 45 | + print(rad_outputFilename) |
| 46 | + delayDisplay("Export results to CSV file: "+rad_outputFilename,3000) |
| 47 | + slicer.util.exportNode(result,rad_outputFilename) |
| 48 | + # Read the csv file into a pandas DataFrame for export to xlsx |
| 49 | + df = pd.read_csv(rad_outputFilename, sep=',') |
| 50 | + excel_file_path =re.sub(r'\.csv$', '.xlsx', rad_outputFilename)# Define the Excel file path where you want to save the data |
| 51 | + # Write the DataFrame to an Excel file |
| 52 | + df.to_excel(excel_file_path, index=False) |
| 53 | + os.remove(rad_outputFilename)#remove original csv file if desired |
| 54 | + |
| 55 | +#savecsvandxlsx('ADC_radiomics','ADC_radiomics') |
| 56 | + |
| 57 | +#################PROCESS ADC VOLUME - find volume using regex################# |
| 58 | +def process_ADC(): |
| 59 | + volnames_original = [] |
| 60 | + #loop through names of volumes in original volume folder and test regex rules: |
| 61 | + children = vtk.vtkIdList() |
| 62 | + shNode.GetItemChildren(originalvols, children) # |
| 63 | + for j in range(children.GetNumberOfIds()): |
| 64 | + child = children.GetId(j) |
| 65 | + #print(child) |
| 66 | + print(shNode.GetItemDataNode(child).GetName())# print items in folder |
| 67 | + volnames_original.append(shNode.GetItemDataNode(child).GetName()) |
| 68 | + for k in range(0,len(volnames_original)): |
| 69 | + if re.search(pattern_ADC, volnames_original[k]): |
| 70 | + print(f'matched volume at {volnames_original[k]} ') |
| 71 | + refvol = getNode(volnames_original[k])#if match is found |
| 72 | + else: |
| 73 | + print('not target volume...') |
| 74 | + #################################RUN RADIOMICS for ADC Original######################33 |
| 75 | + segmentation = getNode('Segmentation') |
| 76 | + table = slicer.mrmlScene.AddNewNodeByClass('vtkMRMLTableNode',f'{refvol.GetName()}_radiomics') |
| 77 | + print(f'applying radiomics to following volume: {refvol.GetName()}') |
| 78 | + delayDisplay(f"applying radiomics to following volume: {refvol.GetName()}") |
| 79 | + logic = SlicerRadiomics.SlicerRadiomicsLogic() |
| 80 | + logic.__init__() |
| 81 | + logic.runSync = True |
| 82 | + logic.runCLIWithParameterFile(refvol,segmentation,table,paramfilepath,callback=lambda: savecsvandxlsx(f'{refvol.GetName()}_radiomics','ADC_radiomics')) |
| 83 | + |
| 84 | +##############RADIOMICS - coreg-skullstripped volumes- isolate relevent volume using regex################### |
| 85 | +def process_coregskullstripped(): |
| 86 | + volnames_skullstripped = [] |
| 87 | + #loop through names of volumes in 'skullstripped' folder and test regex rules: |
| 88 | + children = vtk.vtkIdList() |
| 89 | + shNode.GetItemChildren(subjectItemID, children) # Add a third argument with value True for recursive query |
| 90 | + for L in range(children.GetNumberOfIds()): |
| 91 | + child = children.GetId(L) |
| 92 | + print(child) |
| 93 | + print(shNode.GetItemDataNode(child).GetName())# print items in folder |
| 94 | + volnames_skullstripped.append(shNode.GetItemDataNode(child).GetName()) |
| 95 | + patterns_skullstripped = [pattern_FLAIR,pattern_T1,pattern_T2,pattern_T1C]#list of regext patterns to find volumes #,pattern_T2 |
| 96 | + #################3MAKE TABLES FOR RADIOMICS |
| 97 | + for pattern in patterns_skullstripped:#go through and match each of the patterns to obtain correct reference volume |
| 98 | + for M in range(0,len(volnames_skullstripped)): |
| 99 | + if re.search(pattern, volnames_skullstripped[M]): |
| 100 | + print(f'matched volume at {volnames_skullstripped[M]} ') |
| 101 | + refvol = getNode(volnames_skullstripped[M])#if match is found |
| 102 | + #skullstripvolnamelist.append(volnames_skullstripped[M]) |
| 103 | + global table |
| 104 | + table = slicer.mrmlScene.AddNewNodeByClass('vtkMRMLTableNode',f'{volnames_skullstripped[M]}_radiomics' ) |
| 105 | + logic = SlicerRadiomics.SlicerRadiomicsLogic() |
| 106 | + logic.__init__() |
| 107 | + logic.runSync = True |
| 108 | + logic.runCLIWithParameterFile(refvol,segmentation,table,paramfilepath, callback = exportskullstriptable) |
| 109 | + #tablenames.append(table.GetName()) |
| 110 | + else: |
| 111 | + print('not target volume...') |
| 112 | + |
| 113 | + |
| 114 | +#export tables from the coreg-skullstrip group |
| 115 | +def exportskullstriptable(): |
| 116 | + nm = table.GetName() |
| 117 | + if re.search(pattern_T1, nm):############export tables that match the correct |
| 118 | + savecsvandxlsx(nm,'T1_radiomics') |
| 119 | + print(f'exported {nm} as T1_radiomics') |
| 120 | + elif re.search(pattern_T2, nm): |
| 121 | + savecsvandxlsx(nm,'T2_radiomics') |
| 122 | + print(f'exported {nm} as T2_radiomics') |
| 123 | + elif re.search(pattern_FLAIR, nm): |
| 124 | + savecsvandxlsx(nm,'FLAIR_radiomics') |
| 125 | + print(f'exported {nm} as FLAIR_radiomics') |
| 126 | + elif re.search(pattern_T1C, nm): |
| 127 | + savecsvandxlsx(nm,'T1C_radiomics') |
| 128 | + print(f'exported {nm} as T1C_radiomics') |
| 129 | + else: |
| 130 | + print("No match") |
| 131 | + |
| 132 | +##############################LOOP THROUGH PATIENT FILES############# |
| 133 | +def mainloop(): |
| 134 | + for i in range(0,len(subfolders)): |
| 135 | + global Index |
| 136 | + Index = i #used in savecsvandxlsx() function |
| 137 | + # Construct the complete path to the new subfolder |
| 138 | + table_folder = os.path.join(subfolders[i], "Tables") |
| 139 | + # Create the subfolder |
| 140 | + if not os.path.exists(table_folder): |
| 141 | + os.mkdir(table_folder) |
| 142 | + #find_first mrb file |
| 143 | + scenefile = find_file_with_extension(subfolders[i],'mrb') |
| 144 | + print(f'searching for scene file in {subfolders[i]}') |
| 145 | + #print(i) |
| 146 | + print(f'opening scenefile: {scenefile}') |
| 147 | + #load scene file |
| 148 | + slicer.util.loadScene(scenefile) |
| 149 | + print(f'opened {scenefile}') |
| 150 | + ###################################################Segment statistics export##################################################################### |
| 151 | + import SegmentStatistics |
| 152 | + segmentationNode = getNode('Segmentation') |
| 153 | + segStatLogic = SegmentStatistics.SegmentStatisticsLogic() |
| 154 | + segStatLogic.getParameterNode().SetParameter("Segmentation", segmentationNode.GetID()) |
| 155 | + segStatLogic.computeStatistics() |
| 156 | + #stats = segStatLogic.getStatistics() |
| 157 | + resultsTableNode = slicer.vtkMRMLTableNode() |
| 158 | + slicer.mrmlScene.AddNode(resultsTableNode) |
| 159 | + resultsTableNode.SetName('Segment_statistics') |
| 160 | + segStatLogic.exportToTable(resultsTableNode) |
| 161 | + segStatLogic.showTable(resultsTableNode) |
| 162 | + outputFilename = subfolders[i]+'\\Tables\\'+'CalcVolumes.csv' |
| 163 | + delayDisplay("Export results to CSV file: "+outputFilename) |
| 164 | + segStatLogic.exportToCSVFile(outputFilename) |
| 165 | + # Read the csv file into a pandas DataFrame |
| 166 | + df = pd.read_csv(outputFilename, sep=',') |
| 167 | + excel_file_path =re.sub(r'\.csv$', '.xlsx', outputFilename)# Define the Excel file path where you want to save the data |
| 168 | + # Write the DataFrame to an Excel file |
| 169 | + df.to_excel(excel_file_path, index=False) # Set index=False if you don't want to save the row indices |
| 170 | + os.remove(outputFilename)#remove original csv file if desired |
| 171 | + ################RADIOMICS########################################################################################## |
| 172 | + #For Radiomics: We will employ the "Radiomics" module. |
| 173 | + #Input Image Volumes are as follows: |
| 174 | + #a. Original ADC |
| 175 | + #b. Coregistered-skullstripped T1 |
| 176 | + #c. Coregistered-skullstripped T2 |
| 177 | + #d. Coregistered-skullstripped FLAIR |
| 178 | + #e. Coregistered-skullstripped T1C |
| 179 | + #access segmentation node (should be the only segmentation, named 'Segmentation' across all mrb files) |
| 180 | + global segmentation |
| 181 | + segmentation = getNode('Segmentation') |
| 182 | + ##################access folder hierarchy############################### |
| 183 | + global shNode |
| 184 | + shNode = slicer.mrmlScene.GetSubjectHierarchyNode() |
| 185 | + # Get folder named 'skullstripped' |
| 186 | + global sceneItemID |
| 187 | + sceneItemID = shNode.GetSceneItemID() |
| 188 | + global subjectItemID |
| 189 | + subjectItemID = shNode.GetItemChildWithName(sceneItemID, "skullstripped")#################coreg-skullstripped volumes |
| 190 | + #for access to original ADC: |
| 191 | + global levelunderscened |
| 192 | + levelunderscened = shNode.GetItemByPositionUnderParent(sceneItemID,0) |
| 193 | + global originalvols |
| 194 | + originalvols = shNode.GetItemByPositionUnderParent(levelunderscened,0)######################original volumes |
| 195 | + process_ADC() |
| 196 | + process_coregskullstripped() |
| 197 | + sceneSaveFilename = subfolders[i] + "\\saved-scene-AIAA segmentation_Tables" + time.strftime("%Y%m%d-%H%M%S") + ".mrb" |
| 198 | + if slicer.util.saveScene(sceneSaveFilename): |
| 199 | + logging.info("Scene saved to: {0}".format(sceneSaveFilename)) |
| 200 | + print(f'scene file exported: {sceneSaveFilename}') |
| 201 | + else: |
| 202 | + logging.error("Scene saving failed") |
| 203 | + os.remove(scenefile) |
| 204 | + slicer.mrmlScene.Clear (0)#clear scene |
| 205 | + del Index |
| 206 | + |
| 207 | + |
| 208 | +mainloop() |
| 209 | + |
| 210 | + |
| 211 | + |
| 212 | + |
| 213 | + |
| 214 | + |
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