Skip to content

Hybrid semantic retrieval (core novelty) #146

Description

@cl117

Goal
Add semantic retrieval that keyword/VSEARCH can't do (functionally similar but non-homologous parts).

Tasks

  • Offline-compute text embeddings (name/description) into Typesense.
  • Offline-compute sequence embeddings (DNA model: Nucleotide Transformer / Evo; CDS→protein via ESM-2 as v2), precomputed at index-rebuild (GPU).
  • Implement the fusion layer in Flask: multi-recall (keyword + text-vector + seq-vector) → RRF → log(pagerank+1) re-rank.
  • Evaluate vs old ES baseline on the Phase 0 harness.

Deliverable
Method figure + main results table (the paper's central contribution).

Metadata

Metadata

Assignees

Labels

No labels
No labels

Type

No type

Projects

No projects

Relationships

None yet

Development

No branches or pull requests

Issue actions